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This educational text titled “Basic principles and molecular mechanisms regulating early development of mammals - ¬physiology and pathology“ describes how embryogenesis proceeds in mammals. In this text, students will learn how the egg is fertilised, how the fertilised egg survives in the mother’s womb (called implatation), how the fertilised egg divides, how the blastocyst develops, how the implanted blastocyst undergos gastrulation or the three germ layers form, and how the brain, heart, muscle, and internal organs develop. Moreover, if the processes go awry, what the baby will be affected. This educational material is recommened to General Medical, Dental Medical students and the students who are taking a developmental biological course.