Educational works

Essentials of Medical Chemistry and Biochemistry

Author: Jiří Dostál, Hana Paulová, Eva Táborská, Josef Tomandl

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The English text has been created for one-semester course of medical chemistry. It is assigned for the students of English program of General medicine and Dentistry studies. The textbook summarizes essential facts from chemistry and biochemistry. The selection of topics emphasizes the biochemical processes and the metabolic conversions of compounds occurring in the human body. The knowledge of presented facts is necessary for understanding metabolic processes on cellular and organ level in the following studies of biochemistry

Interactive algorithms in the education of selected acute medicine topics

Author: Petr Štourač, team of students and teachers creating the educational contents of the AKUTNE.CZ portal

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Algorithmization and procedural management of the therapeutic process has become very popular as quality management systems have developed and health care quality has been assessed. It is obvious that a procedurally-thinking physician can react more efficiently, promptly and economically to critical situations which are so abundant in acute medicine. The interactive educational algorithms on the portal AKUTNE.CZ have been developed with the aim of simulating decision processes in acute patients. The ultimate aim of the algorithms is to make students remember the correct procedures which are necessary for the management of acute situations. This comprehensive work contains 24 interactive algorithms both in Czech and English language which deal with various acute medicine topics. It covers acute medicine from prehospital care to highly specialized hospital care.

Molecular biology

Author: Lumír Krejčí

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The terms "recombinant DNA technology", "DNA cloning", "molecular cloning", and "gene cloning" all refer to the same process: a transfer of a DNA fragment of interest from one organism to a self-replicating genetic element such as a bacterial plasmid. The DNA of interest can then be replicated (together with the rest of the plasmid) in a foreign host cell. This technology is a common practice in molecular biology labs today.

Protein preparation

Author: Lumír Krejčí

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This course contains five sub-courses, which consist of theoretical and practical parts. The individual sub-courses should provide students simple and quick approaches needed for solving basic scientific problems that could rise during the course of their bachelor, diploma or PhD study. The first set will allow students to gain knowledge about protein cloning, expression and purification. The second part focuses on biochemical characterization of enzymes via their enzymatic activity as well as protein-protein interactions. The third set will provide simple biochemical methods to detect protein-protein and protein-DNA interactions as well as monitor motor activity of protein.

Medical Assessment Service in the Czech Republic

Author: Petr Brhel, Markéta Petrovová, Libuše Čeledová, Rostislav Čevela a kol.

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Social security is a general name for a system formed by subsystems (or the so called pillars). It is a system of social insurance, system of state social support and system of social assistance. Generally, it can be said that the elementary purpose (and objective) of social security is to help people in difficult life situations that they are not able to handle themselves, or with an assistance of their family or close friends and relatives. These situations are usually accompanied by a drop of or shortfall in an income from gainful activities leading to the loss of funds to provide for basic living needs.

Pathophysiology practicals for General Medicine and Dental Medicine courses

Author: Kateřina Kaňková, Lukáš Pácal, Michal Jurajda, Lydie Izakovičová Hollá, Julie Bienertová Vašků, Michal Masařík, Anna Vašků

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One of the possible approaches to study human diseases and their complexity is to use non-human experimental model organisms.Electronic downloadable textbook “Pathophysiology practicals for General Medicine and Dental Medicine courses“ for students of pathophysiology in General Medicine (VLA) and Dental Medicine (ZLA) courses aims to serve as a practical manual during the practicals and tutorials.

DIOS - Dose Intensity as Oncology Standard

Author: Daniel Klimeš, Ladislav Dušek, Jindřich Fínek, Miroslav Kubásek, Jana Koptíková, Lenka Šnajdrová, Petr Brabec, Jan Novotný Rostislav Vyzula, Jitka Abrahámová, Luboš Petruželka

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The DIOS project was launched in 2006 with the primary objective to enhance the oncologists' awareness of the significance of dose intensity monitoring in anticancer chemotherapy. Another objective was to develop a fully electronic version of chemotherapy regimens which could complement the Principles of Cytostatic Therapy in Malignant Tumours, published by the Czech Oncological Society of CMA JEP. The advantages of the electronic version include easy updates, as well as the possibility of direct use for clinical practice and/or educational purposes. The electronic standards can also be used as templates for hospital information system databases.

Analysis of genomic and proteomic data

Author: Eva Budinská

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This e-learning educational textbook is dedicated to analysis of data from genomic and proteomic high-throughput experiments, such as microarrays, MASS spectrometry, 2-D gel eletrophoresis and DNA sequencing.The book discuss all the important analytical steps from pre-processing through differential gene(protein)-expression to pathways and meta-analysis of multiple experiments. Interactive examples in R and lectures in video format are provided. This educational material contains contributions of different experts in the field from all over the Europe. The content in this e-learning material will be up-dated and extended so that it reflects the latest knowledge in this field.