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Projekt DIOS byl zahájen v roce 2006 s primárním cílem posílit informovanost odborné veřejnosti, která souvisí s významem sledování intenzity dávky protinádorové chemoterapie. Dalším cílem bylo zpracovaní plně elektronické verze chemoterapeutických režimů tak, aby mohla paralelně doplňovat Zásady cytostatické léčby vydávané Českou onkologickou společností ČLS JEP. Hlavní výhodou je nejen snadná aktualizace, ale také možnost přímého využití pro praktické i výukové účely. Elektronické standardy lze rovněž použít jako vzor pro databáze nemocničních informačních systémů.

The DIOS project was launched in 2006 with the primary objective to enhance the oncologists' awareness of the significance of dose intensity monitoring in anticancer chemotherapy. Another objective was to develop a fully electronic version of chemotherapy regimens which could complement the Principles of Cytostatic Therapy in Malignant Tumours, published by the Czech Oncological Society of CMA JEP. The advantages of the electronic version include easy updates, as well as the possibility of direct use for clinical practice and/or educational purposes. The electronic standards can also be used as templates for hospital information system databases.

The electronic textbook "Pediatric oncology for medical students” provides a comprehensive overview of the age-specific differences between pediatric tumors and tumors of the adult age, importance of the age for diagnosis of cancer in childhood, factors influencing treatment decisions and the risks of anticancer therapy.. General section of the textbook provides a concise overview of the fundamental differences between pediatric and adult oncology, age specific clinical presentation of of the most common pediatric tumors, basic diagnostic procedures and treatment modalities of malignant diseases and last but not least the importance of organisation and centralisation of pediatric oncology on national and international level. Special section of the textbook offers an overview of the common and rare malignant tumors in children from epidemiology, etiology, clinical presentation, diagnostic procedures, differential diagnosis to treatment modalities and prognosis. The third section is devoted to emergencies and acute toxicity of anticancer treatment in pediatric oncology. The last section of the textbook offers the review of the most common late consequences and late effects in childhood cancer survivors. The textbook is designed as a basic information of principles and practices in pediatric oncology for pregradual students of medical faculty. The main goal of textbook is the understanding and basic knowledges of the pediatric tumors. Another aim of the textbook is to learn students how to work with literature and literature database search.